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In addition to inducing IKs dysfunction through dominant neg
2019-06-20

In addition to inducing IKs dysfunction through dominant-negative loss-of-function effects and defective channel trafficking, mutations in KCNQ1 suppress IKs channel function by reducing the channel affinity of interacting proteins [68,69]. Phosphatidylinositol-4,5-bisphosphate (PIP2) is a cofactor
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Si se rescata de estas afirmaciones en
2019-06-20

Si se rescata de estas afirmaciones, en primer término, la pretensión crítica realista como fundamento de su propuesta literaria, algunos de los cambios en su entorno cultural cobran relevancia para contextualizar su interés por la ironización de la realidad dentro de la heterogeneidad de su obra. C
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In this context in Heather Zar
2019-06-20

In this context, in , Heather Zar and colleagues report findings from the first study to assess the accuracy of Xpert MTB/RIF in young children presenting to a primary-care facility with symptoms of pulmonary tuberculosis. Primary analysis was done in 309 children in whom four samples (two induced s
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Importa recordar que el intelectual acad mico siempre
2019-06-20

Importa recordar que el intelectual académico siempre se ha sentido incómodo en su propia piel. Leer y escribir rigurosamente pueden ser actos radicales en sí, pero la relación del intelectual y la academia suele exigir sospecha, mucho más que la del artista y el mercado, o la del político y el part
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The fact that interstitial pneumonia was induced
2019-06-19

The fact that interstitial pneumonia was induced at a low dose of bepridil (100mg/day) supports an immunoallergic mechanism rather than a pulmonary toxicity mechanism. In the present case, the dose of bepridil was lower than those in previously reported cases (150–400mg/day) [3] and it was given for
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Lymphocytic infiltrates in thyroid cancer may suggest a back
2019-06-19

Lymphocytic infiltrates in thyroid cancer may suggest a background of chronic lymphocytic thyroiditis. Thyroiditis is characterized by a cellular immune response with dense lymphocytic infiltration of the thyroid gland, as well as by a humoral immune response leading to the production of autoantibod
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In addition evidence of similar resting HR s before
2019-06-19

In addition, evidence of similar resting HR׳s before exercise in the patients and in the controls implies similar autonomic activity at rest during the daytime in both groups of subjects. In contrast, previous studies have reported changes in the nocturnal HR of BrS patients [3,28]. The discrepancy
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No hace falta recordar que esta escena
2019-06-19

No hace falta recordar que esta escena de amenazas, falta de respeto y robos, está lo suficientemente cerca de la realidad fenoménica como para ser reconocido por cualquier ciudadano/a mexicano/a. Estar cerca no significa que las novelas de Mendoza reflejen la realidad, ello sería imposible para cua
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Tobacco use is poised to kill
2019-06-19

Tobacco use is poised to kill as many as 1 billion people in the 21st century, primarily from non-communicable diseases. Less often noted is the effect of tobacco use and second-hand smoke exposure on maternal and child health. Cigarette smoking during pregnancy poses serious risk to the mother and
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We would like to also clarify that we
2019-06-19

We would like to also clarify that we do not underestimate the CIs in our study through the assumption that GDP was observed independently for every child in the survey. The multilevel design and clustering of standard errors at the survey level accounts for the fact that GDP is not observed indepen
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Hill and colleagues estimate that globally
2019-06-19

Hill and colleagues\' estimate that, globally, about 1·5 million (95% CI 1·2–1·8) children aged 5–14 years died in 2010. This finding is somewhat higher than the total estimated by the UN of 1·3 million, although the UN estimate is within the investigators\' CI. However, their estimate is 87% higher
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De esta manera a fines del
2019-06-19

De esta manera, order 1,2-Dilauroyl-sn-glycerol fines del mes de abril y principios del mes de mayo, los temas constantes de Vísperas Republicanas se relacionaron con la conformación del gobierno de Estrada Palma, en la que pesaría más el interés material que el de prestar servicio a la nación: “Din
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Esta autonom a junto a su prop sito
2019-06-19

Esta autonomía, junto NG,NG-dimethyl-L-Arginine hydrochloride su propósito de cambio social y su propuesta de una novedosa perspectiva sobre la política, convierte a los movimientos sociales en una particular fuente de conflicto, incluso en el contexto de estos países estudiados. La conflictividad e
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The mechanism leading to the gelatinous transformation
2019-06-19

The mechanism leading to the gelatinous transformation may involve inhibition of tyrosine kinase activity by tyrosine kinase inhibitors (TKI) leading to blockage of downstream signal pathways, affecting extracellular matrix deposition, adipocyte differentiation and angiogenesis. Moreover, the catabo
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There was a modest excess risk of mortality associated with
2019-06-19

There was a modest excess risk of mortality associated with multidrug-resistant organisms, which was lower than that previously recorded in south Asia. There are methodological challenges in the attribution of excess neonatal mortality with antimicrobial resistance because of known confounding with
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