• The mechanism leading to the gelatinous transformation

  2019-06-19

  

  The mechanism leading to the gelatinous transformation may involve inhibition of tyrosine kinase activity by tyrosine kinase inhibitors (TKI) leading to blockage of downstream signal pathways, affecting extracellular matrix deposition, adipocyte differentiation and angiogenesis. Moreover, the catabo

• There was a modest excess risk of mortality associated with

  2019-06-19

  

  There was a modest excess risk of mortality associated with multidrug-resistant organisms, which was lower than that previously recorded in south Asia. There are methodological challenges in the attribution of excess neonatal mortality with antimicrobial resistance because of known confounding with

• Good news from the Americas illuminated the global health

  2019-06-19

  

  Good news from the Americas illuminated the global health scene in September. As the Ministers of Health from the western hemisphere gathered in Washington, DC, USA, for PAHO\'s 55th Directing Council, a series of announcements confirmed the New World\'s role as a pioneer of sorts in disease prevent

• In Helen Nabwera and colleagues describe how child growth

  2019-06-19

  

  In Helen Nabwera and colleagues describe how child growth in a rural African setting has changed during four decades of public health interventions. The investigators analysed data from an unparalleled resource: longitudinal growth monitoring across three Gambian villages spanning 36 years. The lon

• br Conflict of interest br

  2019-06-19

  

  Conflict of interest Introduction Case report Discussion Dextrocardia is commonly associated with situs inversus totalis (incidence: 2 in 10,000 individuals) and rarely associated with situs solitus (incidence: 1 in 20,000 individuals). While associated cardiac anomalies are seen in appr

• HCV does not kill the cells it infects but triggers

  2019-06-19

  

  HCV does not kill the AR 231453 it infects, but triggers an immune-mediated inflammatory response (hepatitis) that either rapidly clears the infection or slowly destroys the liver, causing the development of HCC and cirrhosis. The outcome is largely determined by the efficiency of the antiviral immu

• It s finally a year by

  2019-06-18

  

  It\'s finally 2015: a year by the end of which extreme poverty and hunger are to be eradicated, maternal and child mortality are to be drastically reduced, and the trajectory of the global incidence of HIV, tuberculosis, and malaria are to be reversed. Much has been written about where the Millenniu

• the The median standardised inclusion score

  2019-06-18

  

  The median standardised inclusion score for the 70 countries reviewed was 1·53 (IQR 0·63–2·09), corresponding to a reasonable level of inclusion. Countries showing best practice (score of 4) were Moldova, Ghana, Serbia, and the Dominican Republic. 20 countries (29%) showed strong inclusion, 25 count

• En textos m s recientes

  2019-06-18

  

  En textos más recientes, Aboy Carlés profundiza esta distinción y reconoce que no toda identidad tiene una pretensión hegemónica y propone distinguir entre identidades totales, identidades parciales e identidades con pretensión hegemónica de acuerdo con el modo de procesar la relación entre la part

• br Discussion Our results confirm

  2019-06-18

  

  Discussion Our results confirm that germline variations in the TPMT gene are associated with treatment outcome in children with ALL [5]. The ability of TPMT to catalyze S-methylation and inactivate 6-mercaptopurine makes it a major determinant of 6-mercaptopurine toxicity. Furthermore, reduced TP

• Results from the present study

  2019-06-18

  

  Results from the present study also showed improvement in timelines for measles immunisation, which is scheduled at 9 months of age, almost a gap of 6 months from the last vaccine according to EPI schedule for LMICs. Although the major focus up until now has been on reminder messages, the impact of

• br Introduction Worldwide trauma is

  2019-06-18

  

  Introduction Worldwide, trauma is currently the sixth leading cause of death, accounting for 10% of mortalities. The urogenital system has consistently been shown to be involved in 10% of patients presenting after trauma and is a significant factor in trauma-induced morbidity and mortality. Renal

• HBeAg positive patients older than years with persistently

  2019-06-18

  

  HBeAg-positive patients older than 40 years with persistently high or high to normal ALT levels may be diagnosed with significant hepatic necroinflammation or fibrosis. During treatment, the clinical significance of timing of HBeAg loss or seroconversion remains unclear. However, a longer duration o

• br Conclusion br Conflict of interest

  2019-06-18

  

  Conclusion Conflict of interest Introduction Loss-of-function mutations in the cardiac sodium (Na+) channel gene have been implicated in Brugada syndrome, progressive cardiac conduction defect (PCCD), sick sinus syndrome, and idiopathic ventricular fibrillation (IVF) [1]. In the present stu

• The results described thus far suggest that PtAF

  2019-06-18

  

  The results described thus far suggest that PtAF-induced atrial remodeling combined with acute atrial stretch facilitates anchoring of 3-D scroll waves to the border of atrial pectinate muscle and prolongs their life span in favor of AF maintenance. However, why is it that scroll waves anchor to the

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