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It is noteworthy that in a recent study Le
2019-06-25
It is noteworthy that in a recent study, Le Scouarnec et al. [199]. estimated the burden of rare coding variation in arrhythmia susceptibility genes among 167 BrS index patients and compared that with 167 individuals ≥65 years old with no history of cardiac arrhythmia. The authors concluded that, ex
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In a recent study Nademanee et al reported
2019-06-25
In a recent study, Nademanee et al. [76]. reported additional evidence pointing to pathologic changes in the RVOT of patients with BrS that have proved undetectable by echocardiography or MRI. In contrast, imaging techniques in ARVC clearly display morphologic and functional changes (e.g., dilation
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The goals of Vision the global initiative to
2019-06-25
The goals of Vision 2020—the global initiative to eliminate avoidable blindness by 2020—include increasing cataract surgical rate and cataract surgical coverage. However, quality must not be sacrificed for quantity. The final visual outcome matters, both to the individual patient and to the communi
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Data continue to show increasing
2019-06-25
Data continue to show increasing numbers of facility-based deliveries with an appreciable decline in both maternal and newborn baby deaths. With nearly half of all births being delivered in low volume, primary health facilities, these facilities clearly fulfill a very crucial role in ensuring that p
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Idelalisib demonstrates a dual mechanism
2019-06-24
Idelalisib demonstrates a dual mechanism of action by inhibiting pro-survival signalling pathways [6], and, like other kinase inhibitors, leads to re-localisation of tumour A 77-01 molecular by blocking ingress into and promoting egress out of the lymph node into the blood. Release from the protect
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Introduction Researchers have long followed the strategy tha
2019-06-24
Introduction Researchers have long followed the strategy that in order to achieve a fuller understanding of the causes of disease and how they can be prevented, it is necessary to study the biochemical and physiological processes involved in the etiology of disease. As I have argued in previous pap
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Cerrone et al reported that the mechanism of
2019-06-24
Cerrone et al. reported that the mechanism of CPVT was due to delayed afterdepolarization‐induced triggered activity in a focal Purkinje network in a knock-in (RyR2) mouse [36]. In addition, chemical ablation of the RV endocardial cavity with Lugol׳s solution, which selectively destroys the Purkinje
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Como es l gico hay un
2019-06-24
Como es lógico, hay un personaje que hace de contrapunto PF-477736 structure esa posición y que por ello mismo la vuelve, por efecto de una diférance (Derrida 1972b), mucho más significativa. Lily, la mujer de Nicolás, no comprende ni lo más mínimo la fascinación que ejerce sobre su marido esa novel
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br Maternal and Child Nutrition Series noted the
2019-06-24
Maternal and Child Nutrition Series noted the emergence of overweight and obesity in low-income and middle-income countries while also documenting the unfinished agenda in undernutrition, sometimes in the same countries and populations. Furthermore, the Series reported analyses of data from Brazil
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met inhibitor Na defini o da Secretaria Nacional de Pol tica
2019-06-24
Na definição da Secretaria Nacional de Políticas de Promoção da Igualdade Racial, vinculada atualmente ao Ministério dos Direitos Humanos do governo federal, as ações afirmativas são políticas públicas que têm como objetivo met inhibitor correção de desigualdades raciais acumuladas ao longo dos anos
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br Conflict of interest br Introduction
2019-06-21
Conflict of interest Introduction Over the last several decades, substantial research interest has been focused on characterizing the pathophysiological substrate underlying atrial fibrillation (AF) [1]. AF is a complex arrhythmia and has been shown to be temporally variable, so that AF durati
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br An estimated million babies are born preterm annually Pre
2019-06-21
An estimated 15 million babies are born preterm annually. Preterm birth complications account for more than 15% of deaths in children younger than 5 years and survivors often have long-term consequences with respect to their health, growth, and psychosocial functioning. The most beneficial interve
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La pregunta que fundamenta esta investigaci n es acerca de
2019-06-21
La pregunta que fundamenta esta investigación es acerca de la posibilidad de que los participantes de experiencias de acción colectiva urbana definan y re-definan sus pertenencias NBI 27914 hydrochloride la región y las naciones en las que se insertan. Este acercamiento a las representaciones que lo
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br Contribution br Acknowledgments and disclosures br Introd
2019-06-21
Contribution Acknowledgments and disclosures Introduction Following HSCT a complex immune reconstitution (IR) is observed. When the infused CD34+cells (CD34+i) begin to proliferate, an increase in peripheral blood BAY 41-8543 is detected. Lymphocytes require more time than granulocytes in o
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Evidence of the efficacy of topiramate in PTC
2019-06-21
Evidence of the efficacy of topiramate in PTC has been reported in the literature [41,42]. The largest study, an open-label trial by Celebisoy and colleagues [41], demonstrated the non-inferiority of topiramate to acetazolamide in the management of idiopathic intracranial proteases in a population
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